Selected publications
Schulte AJ, Lewellen M, Durose W, Nolan E, Taghizadeh L, Todhunter D, Bush C, Lang HP, Brown ME, DePauw TA, Makielski KM, Kim JH, et al. Remodeling the Sarcoma Microenvironment by Simultaneous Targeting of Urokinase Type Plasminogen Activator Receptors and Epidermal Growth Factor Receptors to Promote Antitumor Activity. J Pharmacol Exp Ther. 2025 In Press. doi: 10.1016/j.jpet.2025.103674.
Kim JH, Lee D, Hall K, Jo H, Bannantine JP, Davis WC, de Souza C. Major membrane protein of Mycobacterium avium subp. paratuberculosis activates immune and autophagic pathways in bovine monocyte-derived macrophages. Vet Immunol Immunopathol. 2025 Apr;282:110901. doi: 10.1016/j.vetimm.2025.110901. PMID: 40015107.
Lee D, Kozurek EC, Abdullah M, Wong EJ, Li R, Liu ZS, Nguyen HD, Dickerson EB, Kim JH. PIK3CA mutation fortifies molecular determinants for immune signaling in vascular cancers. Cancer Gene Ther. 2025 Feb;32(2):254-267. doi: 10.1038/s41417-024-00867-4. PMID: 39709507.
Kim JH, Schulte AJ, Sarver AL, Lee D, Angelos MG, Frantz AM, Forster CL, O’Brien TD, Cornax I, O’Sullivan MG, Cheng N, Lewellen M, Oseth L, Kumar S, Bullman S, Pedamallu CS, Goyal SM, Meyerson M, Lund TC, Breen M, Lindblad-Toh K, Dickerson EB, Kaufman DS, Modiano JF. Hemangiosarcoma Cells Promote Conserved Host-derived Hematopoietic Expansion. Cancer Res Commun. 2024 Jun 11;4(6):1467-1480. doi: 10.1158/2767-9764.CRC-23-0441. PMID: 38757809.
; 16(7):1389. doi: doi.org/10.3390/cancers16071389. PMID: 38611067.
Rad R, Daul B, Glass P, Joh R, Pemberton C, Shar A, Kim JH, Joung D. 3D Printed Magnet-Infused Origami Platform for 3D Cell Culture Assessments. Advanced Materials Technologies. 2023 Apr 24;8(8), 2202204. doi: 10.1002/admt.202202204.
Makielski KM, Fox LE, Johannes CM, Rendahl AK, Schulte AJ, Kim JH, et al. Evaluation of coated platelets, a subset of highly procoagulant platelets, in healthy dogs and dogs with neoplasia. Am J Vet Res. 2022 Aug 18;83(10). doi: 10.2460/ajvr.22.03.0042. PMID: 35973003.
Namgong C, Kim JH, Lee MH, Midkiff D. Non-invasive cancer detection in canine urine through Caenorhabditis elegans chemotaxis. Front Vet Sci. 2022;9:932474. doi: 10.3389/fvets.2022.932474. eCollection 2022. PMID: 36016810.
Jeon HJ, Choi HS, Keum B, Bang EJ, Lee KW, Kim SH, Yim SY, Lee JM, Kim ES, Seo YS, Jeen YT, Lee HS, Chun HJ, Kim HB, Kim JH. Feasibility and effectiveness of endoscopic irreversible electroporation for the upper gastrointestinal tract: an experimental animal study. Sci Rep. 2021 Jul 28;11(1):15353. doi: 10.1038/s41598-021-94583-w. PMID: 34321494.
Cheng N, Schulte AJ, Santosa F, Kim JH. Machine learning application identifies novel gene signatures from transcriptomic data of spontaneous canine hemangiosarcoma. Brief Bioinform. 2021 Jul 20;22(4). doi: 10.1093/bib/bbaa252. PMID: 33078825.
Kim JH, Megquier K, Thomas R, Sarver AL, et al. Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions. Mol Cancer Res. 2021 May;19(5):847-861. doi: 10.1158/1541-7786.MCR-20-0937. PMID: 33649193.
Saha J, Kim JH, Amaya CN, Witcher C, et al. Propranolol Sensitizes Vascular Sarcoma Cells to Doxorubicin by Altering Lysosomal Drug Sequestration and Drug Efflux. Front Oncol. 2020;10:614288. doi: 10.3389/fonc.2020.614288. eCollection 2020. PMID: 33598432.
Kim JH. PIK3CA mutations matter for cancer in dogs. Res Vet Sci. 2020 Dec;133:39-41. doi: 10.1016/j.rvsc.2020.09.001. Review. PMID: 32932196.
Kim JH. Interleukin-8 in the Tumor Immune Niche: Lessons from Comparative Oncology. Adv Exp Med Biol. 2020;1240:25-33. doi: 10.1007/978-3-030-38315-2_2. Review. PMID: 32060885.
Megquier K, Turner-Maier J, Swofford R, Kim JH, et al. Comparative Genomics Reveals Shared Mutational Landscape in Canine Hemangiosarcoma and Human Angiosarcoma. Mol Cancer Res. 2019 Dec;17(12):2410-2421. doi: 10.1158/1541-7786.MCR-19-0221. PMID: 31570656.
Langsten KL, Kim JH, Sarver AL, Dewhirst M, Modiano JF. Comparative Approach to the Temporo-Spatial Organization of the Tumor Microenvironment. Front Oncol. 2019;9:1185. doi: 10.3389/fonc.2019.01185. eCollection 2019. Review. PMID: 31788448.
Kim JH, Frantz AM, Sarver AL, Gorden Klukas BH, et al. Modulation of fatty acid metabolism and immune suppression are features of in vitro tumour sphere formation in ontogenetically distinct dog cancers. Vet Comp Oncol. 2018 Mar;16(1):E176-E184. doi: 10.1111/vco.12368. PMID: 29152836.
Im KS, Graef AJ, Breen M, Lindblad-Toh K, Modiano JF, Kim JH. Interactions between CXCR4 and CXCL12 promote cell migration and invasion of canine hemangiosarcoma. Vet Comp Oncol. 2017 Jun;15(2):315-327. doi: 10.1111/vco.12165. PMID: 26337509.
Borgatti A, Koopmeiners JS, Sarver AL, Winter AL, Stuebner K, Todhunter D, Rizzardi AE, Henriksen JC, Schmechel S, Forster CL, Kim JH, et al. Safe and Effective Sarcoma Therapy through Bispecific Targeting of EGFR and uPAR. Mol Cancer Ther. 2017 May;16(5):956-965. doi: 10.1158/1535-7163.MCT-16-0637. PMID: 28193671.
Im KS, Kim JH, Graef AJ, Cornax I, et al. Establishment of a Patient-Derived Xenograft of Canine Enteropathy-Associated T-Cell Lymphoma, Large Cell Type. J Comp Pathol. 2017 Jan;156(1):37-41. doi: 10.1016/j.jcpa.2016.11.271. PMID: 28011041.
Song JM, Anandharaj A, Upadhyaya P, Kirtane AR, Kim JH, et al. Honokiol suppresses lung tumorigenesis by targeting EGFR and its downstream effectors. Oncotarget. 2016 Sep 6;7(36):57752-57769. doi: 10.18632/oncotarget.10759. PMID: 27458163.
Kim JH, Furrow E, Ritt MG, Utz PJ, et al. Anti-Insulin Immune Responses Are Detectable in Dogs with Spontaneous Diabetes. PLoS One. 2016;11(3):e0152397. doi: 10.1371/journal.pone.0152397. eCollection 2016. PMID: 27031512.
Kim JH, Graef AJ, Dickerson EB, Modiano JF. Pathobiology of Hemangiosarcoma in Dogs: Research Advances and Future Perspectives. Vet Sci. 2015 Nov 6;2(4):388-405. doi: 10.3390/vetsci2040388. Review. PMID: 29061949.
Im KS, Jang YG, Shin JI, Kim NH, Lim HY, Lee SM, Kim JH, Sur JH. CD44+/CD24- Cancer Stem Cells Are Associated With Higher Grade of Canine Mammary Carcinomas. Vet Pathol. 2015 Nov;52(6):1041-4. doi: 10.1177/0300985815593121. PMID: 26173453.
Rodriguez AM, Graef AJ, LeVine DN, Cohen IR, Modiano JF, Kim JH. Association of Sphingosine-1-phosphate (S1P)/S1P Receptor-1 Pathway with Cell Proliferation and Survival in Canine Hemangiosarcoma. J Vet Intern Med. 2015 Jul-Aug;29(4):1088-97. doi: 10.1111/jvim.13570. PMID: 26118793.
Tonomura N, Elvers I, Thomas R, Megquier K, Turner-Maier J, Howald C, Sarver AL, Swofford R, Frantz AM, Ito D, Mauceli E, Arendt M, Noh HJ, Koltookian M, Biagi T, Fryc S, Williams C, Avery AC, Kim JH, et al. Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers. PLoS Genet. 2015 Feb;11(2):e1004922. doi: 10.1371/journal.pgen.1004922. eCollection 2015 Feb. PMID: 25642983.
Kim JH, Frantz AM, Anderson KL, Graef AJ, et al. Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment. Exp Cell Res. 2014 Apr 15;323(1):155-164. doi: 10.1016/j.yexcr.2014.02.020. PMID: 24582862.
Gorden BH, Kim JH, Sarver AL, Frantz AM, et al. Identification of three molecular and functional subtypes in canine hemangiosarcoma through gene expression profiling and progenitor cell characterization. Am J Pathol. 2014 Apr;184(4):985-995. doi: 10.1016/j.ajpath.2013.12.025. PMID: 24525151.
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